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CRISERNA: Genome Editing for Ethical Innovation

A project by: Muharrem Okan cakir

£70
pledged of £3,000 target
2%
FUNDED
1
USERS
We’re building the world’s first ethical genome editing simulation platform. Join the evolution.

🔬 A short summary of our project

We're raising £3,000 to develop the first ethical genome editing simulation platform—a space where science meets responsibility. CRISERNA allows researchers, students, and innovators to simulate gene editing experiments and evaluate ethical outcomes before stepping into the lab. Your support will help build this revolutionary tool and bring genome editing into a more conscious and transparent future.

👥 Who are we?

We’re a multidisciplinary team of scientists, educators, and innovators with expertise spanning cancer research, genome editing, bioinformatics, and ethical AI. Our project is led by:

Dr. Muharrem Okan Cakir – Cancer Therapeutics Researcher, Founder of CRISERNA, with expertise in 3D organoid modelling, genome editing, and bioethics.

Prof. Mustafa Özdoğan – Consultant Oncologist and visionary clinical researcher, contributing deep insight into translational oncology and personalized medicine.

Prof. Betül Karademir Yılmaz – Expert in organoid systems and omics technologies, with a strong background in 3D culture and translational bioengineering.

Prof. Uğur Bilge – Data scientist and academic leader with extensive experience in systems biology, bioinformatics, and AI-driven gene target discovery.

Together, our mission is to build a platform where innovation and responsibility meet, shaping the future of genome editing through simulation, education, and ethics.

📖 Our story

Gene editing is transforming science—but without ethical foresight, its power could outpace our wisdom. That’s why we’re creating CRISERNA: the first platform to model genome editing procedures with built-in ethical assessment tools, powered by AI.

We believe that before editing life’s code, we must ask: “Not just what can we do, but what should we do?”

  • Our project is unique because it blends:
  • Interactive CRISPR-Cas9 simulations
  • Predictive off-target and phenotypic modeling
  • Ethical risk scoring
  • Visualisation of genome edits and downstream effects

We aim to educate, inform, and empower anyone who interacts with gene editing—researchers, educators, policymakers, and students.

🎯 What are we doing and why?

Gene editing is no longer science fiction—it’s now in classrooms, labs, and clinics. Yet very few tools help users understand the real-world consequences before making a change to DNA.

By supporting this project, you’re helping to:

  • Build a safer future for genetics
  • Democratise access to responsible CRISPR tools
  • Educate the next generation of ethical scientists

Your impact will help prevent irresponsible experiments, ensure ethical foresight, and create an open, visual, and accessible simulation environment for all.

💡 How will you be helping?

Every donation makes a difference! The funds we raise will support key parts of our project; they will be distributed across the following categories:

🔹 Platform Development & Hosting (£1,200) To cover initial software setup, secure cloud hosting, and server costs for running CRISERNA simulations.

🔹 Toolkit Design (£800) For creating the educational toolkit  including explainer infographics, teaching modules, visual/graphic design support, and publishing (both digital and printed formats).

🔹 Prototype Module Build (£700) To build the first functional CRISERNA simulation module, integrate AI-based off-target prediction, and set up a testing environment.

🔹 Communication & Outreach (£300) For campaign video, explainer graphics, and outreach materials to share the project with students, researchers, and institutions.

❗️Please Note: All pricing is rounded to approximate values, as they are not final. However, the listed figures represent the estimated minimum funding required to complete the CRISERNA prototype and toolkit.

💸 Where will the money go?

🎯 If we hit our minimum target (£0–£1000):
  • Basic CRISPR-Cas9 simulation engine
  • Ethics module prototype
  • Platform domain + server setup
  • Basic design and outreach toolkit
💡 If we reach our full target (£3,000):
  • Launch full interactive platform (beta)
  • Develop AI-powered off-target prediction
  • Create 3 educational modules (for schools & universities)
  • Partner with institutions for pilot testing
  • Deliver rewards and outreach sessions
🚀 If we go beyond our goal:
  • Add plant and animal genome editing modules
  • Build an ethics-CRISPR decision tree
  • Translate the platform into 3 languages
  • Offer free workshops to 10 underfunded schools

🔄 Updates

We'll post bi-weekly updates throughout the campaign and development process. Supporters will get behind-the-scenes previews, platform demos, and development progress. You’ll be part of the journey as we build a truly novel digital solution.

🎁 Rewards

We’ve got some fab rewards to thank everyone who donates—whether it's £5 or £500.

From supporter shout-outs to early beta access and personalised gene-editing scenario visualisations, there’s something for everyone. Check them out on the side! 

🌐 Find us here

LinkedIn | Substack | Linktree

👉 Follow us for regular updates, sneak peeks, and behind-the-scenes content!

Help us succeed!

You don’t need to donate to support this mission (though we’d love it if you did!). You can help by:

- Sharing this project with your friends, colleagues, and network

- Tagging us on LinkedIn, Instagram, or wherever you engage

- Talking about CRISERNA in a class, lab, or even over coffee

Every share makes a difference. Every pound brings us closer to building a safer, more ethical genetic future.

Let’s build it together.